Method of determining toxicity of an immunomodulatory drug for use in humans

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专利权人:

The Jackson Laboratory

发明人:

Keck, James,Ye, Chunting

申请号：

AU2018254420

公开号：

AU2018254420A1

申请日:

2018.04.17

申请国别(地区):

AU

年份:

2019

代理人:

摘要：

Humanized mouse models and methods are provided for determining whether administration of an immunomodulatory drug likely elicits a severe cytokine release syndrome in a human. Humanized mouse models and methods are also provided for determining the immunotoxicity in a human of a drug candidate or of drug combinations.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/