Anders Pettersson,Christer Nyström,Susanne Bredenberg
申请号:
US11666361
公开号:
US09265720B2
申请日:
2005.10.26
申请国别(地区):
US
年份:
2016
代理人:
摘要:
There is provided a formulation suitable for transmucosal administration comprising a short acting hypnotic drug, which formulation provides a measurable plasma concentration of drug within 10 minutes of administration. The formulation is capable of providing sleep on demand, and preferably comprises particles of drug, for example zolpidem or a pharmaceutically-acceptable salt thereof and a mucoadhesion promoting agent, such as sodium carboxymethylcellulose, which particles of drug and mucoadhesive are presented upon the surface of larger carrier particles.