Rajinder Singh,Ankush Argade,Donald G. Payan,Susan Molineaux,Sacha J. Holland,Jeffrey Clough,Holger Keim,Somasekhar Bhamidipati,Catherine Sylvain,Hui Li,Alexander B. Rossi
申请号：
US14309530
公开号：
US09133133B2
申请日:
2014.06.19
申请国别(地区):
US
年份:
2015
代理人:
摘要：
The present invention provides 2,4-pyrimidinediamine compounds that inhibit the IgE and/or IgG receptor signaling cascades that lead to the release of chemical mediators, intermediates and methods of synthesizing the compounds and methods of using the compounds in a variety of contexts, including in the treatment and prevention of diseases characterized by, caused by or associated with the release of chemical mediators via degranulation and other processes effected by activation of the IgE and/or IgG receptor signaling cascades.
