OLIGOMERIZATION DOMAIN OF P53 TO BYPASS THE DOMINANT-NEGATIVE EFFECT OF MUTANT

• 收藏
• 分享

专利权人:

University of Utah Research Foundation

发明人:

LIM, Carol,OKAL, Abood

申请号：

EP15746473

公开号：

EP3102221A4

申请日:

2015.02.06

申请国别(地区):

EP

年份:

2017

代理人:

摘要：

Disclosed are peptides comprising a partial p53 peptide and a mutated Bcr coiled-coil domain. Also disclosed are nucleic acid sequences capable of encoding a peptide comprising a partial p53 peptide and a mutated Bcr coiled-coil domain. The disclosed peptides and nucleic acid sequences can be used to treat cancer, suppress tumor activity and induce apoptosis.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/