Christopher W. Cianci,Samuel Gerritz,Sean Kim,David R. Langley,Guo Li,Bradley C. Pearce,Annapurna Pendri,Shuhao Shi,Weixu Zhai,Shirong Zhu
申请号：
US13242676
公开号：
US20120245176A1
申请日:
2011.09.23
申请国别(地区):
US
年份:
2012
代理人:
摘要：
A compound of Formula I is set forth, including pharmaceutically acceptable salts thereof:wherein Het is a 5 or 6-membered heterocycle with —N, —O, or —S adjacent to the —Ar substituent or adjacent to the point of attachment for the —Ar substituent Ar is aryl or heteroaryl R is —CH3, —CH2F, —CHF2 or —CH═CH2 V is —H, —CH3 or ═O W is —NO2, —Cl, —Br, —CH2OH, or —CN X is —Cl, —Br, —F, —CH3, —OCH3, or —CN Y is —CH or —N and Z is —CH or —N.This compound is useful in compositions for the prevention and treatment of influenza virus.
