GUNZNER, JANET L.,SUTHERLIN, DANIEL P.,STANLEY, MARK S.,BAO, LIANG,CASTANEDO, GEORGETTE,LALONDE, REBECCA L.,WANG, SHUMEI,REYNOLDS, MARK E.,SAVAGE, SCOTT J.,MALESKY, KIMBERLY,DINA, MICHAEL S.
申请号:
PL09731060
公开号:
PL2271642T3
申请日:
2009.04.10
申请国别(地区):
PL
年份:
2014
代理人:
摘要:
The invention provides novel inhibitors of hedgehog signaling that are useful as a therapeutic agents for treating malignancies where the compounds have the general formula I: wherein A, X, Y R1, R2, R3, R4, m and n are as described herein.