James M. Wells,Carey Lane Watson,Jorge Orlando Munera,Maxime Mickael Mahe,Michael A. Helmrath,Michael J. Workman
申请号：
US15515840
公开号：
US20170292116A1
申请日:
2015.10.16
申请国别(地区):
US
年份:
2017
代理人:
摘要：
Disclosed are methods for making a vascularized hollow organ derived from human intestinal organoid (HIOs). The HIOs may be obtained from human embryonic stem cells (ESC's) and/or induced pluripotent stem cells (iPSCs), such that the HIO forms mature intestinal tissue. Also disclosed are methods for making a human intestinal tissue containing a functional enteric nervous system (ENS).
