MASSACHUSETTS INSTITUTE OF TECHNOLOGY;THE GENERAL HOSPITAL CORPORATION
发明人:
INDOLFI, LAURA,EDELMAN, ELAZER R.,LANGER, ROBERT S.,CLARK, JEFFREY W.,TING, DAVID T.,FERRONE, CRISTINA ROSA ANNAMARIA,LIGORIO, MATTEO
申请号：
CA2944480
公开号：
CA2944480A1
申请日:
2014.04.10
申请国别(地区):
CA
年份:
2014
代理人:
摘要：
Drug-eluting devices and methods for the treatment of tumors of the pancreas, biliary system, gallbladder, liver, small bowel, or colon, are provided. Methods include deploying a drug-eluting device having a film which includes a mixture of a degradable polymer and a chemotherapeutic drug, wherein the film has a thickness from about 2 µm to about 1000 µm, into a tissue site and releasing a therapeutically effective amount of the chemotherapeutic drug from the film to treat the tumor, wherein the release of the therapeutically effective amount of the drug from the film is controlled by in vivo degradation of the polymer at the tissue site.
