REDER, ROBERT, F.,GOLDENHEIM, PAUL, D.,KAIKO, ROBERT, F.
申请号:
HK11107538.1
公开号:
HK1153377B
申请日:
2011.07.19
申请国别(地区):
HK
年份:
2013
代理人:
摘要:
A sustained release formulation of buprenorphine is new. The composition comprises a transdermal delivery device which provides a first order release of buprenorphine over a 3-day dosing interval so that a maximum plasma concentration of 20 10 1052 pg/ml is obtained. the device then provides zero order kinetics over at least 2 more days.