PROBLEM TO BE SOLVED: To provide a medicine for prevention or treatment of diabetes or obesity, which has a GK activation effect.SOLUTION: The medicine contains as an effective component, a 2-pyridone compound of formula [1] (wherein A represents a benzene or pyridine ring X represents either structure shown in formula [3] V represents a single bond etc. and W is a single bond, ether bond or the like).COPYRIGHT: (C)2013,JPO&INPIT【課題】GK活性化作用を有する糖尿病又は肥満の予防又は治療薬の提供。【解決手段】式[1]式[1]中、Aで示される環はベンゼン環、又はピリジン環を示し、Xは、下記に示す式[3]で表されるいずれかの構造を示し、Vは単結合などを示し、Wは単結合、エーテル結合などで表される2-ピリドン化合物。【選択図】なし