Pharmaceutical composition comprising a compound Derivative of (6S) - 6 - (2 - hydroxy - 2-methylpropyl) - phenyl - 3 - 6 - [(1S) - 1 - [4 - (2 - oxo - 1.2 - dihidropiridin - 4-yl) phenyl] ethyl} - 1.3 - oxazin - 2 - ona and a Second Therapeutic Agent and its use to prevent or delay a disorder associated with Diabetes mellitus 2 or tolerate Cia impaired glucose.
The invention relates to a pharmaceutical composition comprising 1.a and/or 1.b according to claim 1 in combination with at least one second therapeutic agent 2 which is suitable in the treatment or prevention of one or more conditions selected from type 1 diabetes mellitus, type 2 diabetes mellitus, impaired glucose tolerance and hyperglycemia. In addition the present invention relates to methods for preventing or treating of metabolic disorders and related conditions.COMPOSICION FARMACEUTICA QUE COMPRENDE UN COMPUESTO DERIVADO DE (6S)-6-(2-HIDROXI-2-METILPROPIL)-6-FENIL-3-{(1S)-1-[4-(2-OXO-1,2-DIHIDROPIRIDIN-4-IL)FENIL]ETIL}-1,3-OXAZIN-2-ONA Y UN SEGUNDO AGENTE TERAPÉUTICO; Y SU USO PARA PREVENIR O RETRASAR UN TRASTORNO ASOCIADO A DIABETES MELLITUS 2 O TOLERANCIA ALTERADA A LA GLUCOSA.