The invention relates to a cuff (20) for determining a physiological parameter, said cuff comprising a photoplethysmograph arranged with an emitter (6) for emitting a radiation in a direction of a tissue to be investigated, a detector (5) for detecting the radiation from the tissue and an inflatable bladder (8) for transferring pressure to the tissue, said inflatable bladder comprising a back-layer (8″) and a top-layer (8′), wherein the top-layer is conceived to be brought into contact with the tissue, the top-layer being substantially more flexible than the back-layer. The invention further relates to a measurement system.