(57)< Abstract > This invention halts the internal organs, conservation, and/or being the manner which is retained, (1) kalium channel aperture medicine or agonisuto of the effective tonnage and/or adenosine receptor agonisuto and (2) the local anesthetic, regards the manner which includes the fact that it prescribes in the patient who needs that. This invention (1) kalium channel aperture medicine or agonisuto of the effective tonnage and/or had the fact that the constituent which includes with adenosine receptor agonisuto and (2) the local anesthetic is added to the internal organs, it halts the internal organs, conservation, and/or it regards also the manner which is retained. This invention, furthermore, (1) kalium channel aperture medicine or agonisuto of the effective tonnage and/or pharmacy includes with adenosine receptor agonisuto and (2) the local anesthetic or offers the veterinarian constituent.本発明は、臓器を停止し、保護し、及び/又は保存する方法であって、有効量の(1)カリウムチャンネル開口剤又はアゴニスト及び/又はアデノシン受容体アゴニストと(2)局所麻酔剤とを、それを必要とする患者に投与とすることを含む方法に関する。本発明は、有効量の(1)カリウムチャンネル開口剤又はアゴニスト及び/又はアデノシン受容体アゴニストと(2)局所麻酔剤とを含む組成物を臓器に加えることを備えた、臓器を停止し、保護し、及び/又は保存する方法にも関する。本発明は、さらに、有効量の(1)カリウムチャンネル開口剤又はアゴニスト及び/又はアデノシン受容体アゴニストと(2)局所麻酔剤とを含む薬学的又は獣医組成物を提供する。