您的位置: 首页 > 农业专利 > 详情页

使用CHK1和ATR抑製劑的組合治療癌症的方法
专利权人:
发明人:
申请号:
HK17110752.8
公开号:
HK1236827A
申请日:
2017.10.23
申请国别(地区):
HK
年份:
2018
代理人:
摘要:
The present invention relates to methods of treating cancer in a patient by administering a compound useful as an inhibitor of ATR protein kinase in combination with a compound useful as an inhibitor of Chkl protein kinase. The aforementioned combination displays a surprising synergistic effect in treating cancer despite the targeted protein kinases being within the same biological pathway. Moreover, the present invention also relates to methods of treating cancer by administering a compound useful as an inhibitor of ATR protein kinase; administering a compound useful as an inhibitor of Chkl protein kinase; as well as administering a DNA damaging agent to a patient. The compounds utilized in this invention are represented by formula (I) and formula (II): wherein the variables are as defined herein.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

意 见 箱

匿名:登录

个人用户登录

找回密码

第三方账号登录

忘记密码

个人用户注册

必须为有效邮箱
6~16位数字与字母组合
6~16位数字与字母组合
请输入正确的手机号码

信息补充