The present invention contemplates compositions comprising compounds, inparticular dihydroeugenol (DHE)and/or isoeugenol (IE) and/or ethyl vanillin (EV) or salts, esters, ethers, orderivatives thereof, and methods for topically orsystemically delivering them for treatment against inflammation-related andother dermatological conditions such as described herein.These DHE and/or IE and/or EV or salts, esters, ethers or derivatives thereofalso are delivered to a measurable extent transepidermallyor transdermally and thus may have systemic and/or localized anti-inflammatory effects within the body. In one of its methodaspects, this invention is directed to a method for treating a patient with adermatological disease or condition by topically administeringto said patient a pharmaceutical or cosmetic composition comprising apharmaceutically or cosmetically acceptable topicalcarrier and an effective dermatological disease, disorder or condition-treating amount of a formulation of DHE and/or IE and/or EV,or salts, esters, ethers, or derivatives thereof. In particular, the presentinvention is directed to a method of using a composition comprisingone or more of DHE and/or IE and/or EV or salts, esters, ethers, orderivatives for treating dermatologic diseases, disordersor conditions, aging effects related to decreasing production of collagen,elastin, or hyaluronic acid, or to hyperpigmentation. Theformulations may further contain cinnamaldehyde.
