The new microbe which is the production germ of new chemical compound, and those production manners, and the aforementioned new chemical compound which possess enzyme inhibition activity vis-a-vis the anti-bacterial activity which is superior by inhibiting two component control systems of the bacterium, vis-a-vis wide pathogenic bacterium such as medicine tolerance germ and plant pathogenic bacterium, or the enzyme which the aforementioned bacterium has, and the chemical compound content constituent which utilizes aforementioned new chemical compound, it designates that the anti-bacterial medicine, and the enzyme active inhibiter are offered as purpose. It is displayed with the below-mentioned constitutional formula (1) chemical compound and the below-mentioned constitutional formula which feature that chemical compound, and the streptomyces which feature that it is displayed with (2) (Streptomyces) it belongs to being attached, production manner and the like extracts aforementioned chemical compound from the culture which is obtained with culture process and the aforementioned culture process which culture the microbe which possesses the capacity which produces aforementioned chemical compound of the aforementioned chemical compound which features that the picking process are included it offers.< Conversion 11 >< Conversion 12 >細菌の二成分制御系を阻害することにより、薬剤耐性菌、植物病原細菌等の幅広い病原性細菌に対し、優れた抗菌活性、若しくは、前記細菌の有する酵素に対し、酵素阻害活性を有する新規化合物、及びそれらの製造方法、並びに、前記新規化合物の生産菌である新規微生物、及び前記新規化合物を利用した化合物含有組成物、抗菌剤、及び酵素活性阻害剤を提供することを目的とする。 下記構造式(1)で表されることを特徴とする化合物、下記構造式(2)で表されることを特徴とする化合物、及び、ストレプトマイセス(Streptomyces)属に属し、前記化合物を生産する能力を有する微生物を培養する培養工程と、前記培養工程で得られた培養物から前記化合物を採取する採取工程とを含むことを特徴とする前記化合物の製造方法などを提供する。【化11】【化12】
