具人類化分化47基因群的非人類動物

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专利权人:

REGENERON PHARMACEUTICALS; INC.

发明人:

GURER, CAGAN,IOFFE, ELLA,MUJICA, ALEXANDER,THURSTON, GAVIN

申请号：

HK16114307.1

公开号：

HK1225912A

申请日:

2016.12.15

申请国别(地区):

HK

年份:

2017

代理人:

摘要：

Non-human animals, and methods and compositions for making and using the same, are provided, wherein said non-human animals comprise a humanization of an endogenous cluster of differentiation (CD) gene, in particular a humanization of a CD47 gene. Said non-human animals may be described, in some embodiments, as having a genetic modification to an endogenous CD47 gene so that said non-human animals express a CD47 polypeptide that includes a human portion and a non-human portion (e.g., a murine portion).

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/