According to an aspect of the present invention,A kind of equipment treated with what and/or prevent disease of cornea is provided,The equipment includes :-applicator head,The applicator head includes the radiation source that can excite non-toxic substance; And-controller,It can be operated with excitation radiation source radiation; Wherein meet at least one of following two condition :-applicator head includes first sensor,First sensor can measure signal of the base what applicator head with respect to the position of what cornea; Applicator head is configured as being physically contacted with cornea; And wherein the controller can be operated with base what respectively by the signal of sensor measurement come excitation radiation source radiation or the excitation radiation source when applicator head touches cornea.根據本發明的一個方面,提供了一種用於治療和/或預防角膜疾病的設備,該設備包括:-施加器頭,該施加器頭包括能够激發非毒性物質的輻射源;以及-控制器,其可操作以激勵輻射源輻射;其中滿足以下兩個條件中的至少一個:-施加器頭包括第一傳感器,第一傳感器能够測量基於施加器頭相對於角膜的位置的信號;-施加器頭被配置爲與角膜物理接觸;以及其中所述控制器可操作以分別基於由傳感器測量的信號來激勵輻射源輻射或在施加器頭觸碰到角膜時激勵輻射源。