Antonio Campos-Neto,Yasir Skeiky,Pamela Ovendale,Shyian Jen,Michael Lodes
申请号：
US14849531
公开号：
US20160222070A1
申请日:
2015.09.09
申请国别(地区):
US
年份:
2016
代理人:
摘要：
Compounds and methods for diagnosing tuberculosis or for inducing protective immunity against tuberculosis are disclosed. The compounds provided include polypeptides that contain at least one immunogenic portion of one or more Mycobacterium proteins and DNA molecules encoding such polypeptides. Diagnostic kits containing such polypeptides or DNA sequences and a suitable detection reagent may be used for the detection of Mycobacterium infection in patients and biological samples. Antibodies directed against such polypeptides are also provided. In addition, such compounds may be formulated into vaccines and/or pharmaceutical compositions for immunization against Mycobacterium infection.
