SHIPOV, VALERY PAVLOVICH,PIGAREV, EVGENY SERGEEVICH,FEDOROS, ELENA IVANOVNA,TROFIMOVA, NADEZHDA PETROVNA
申请号：
EP06733213
公开号：
EP1864673A4
申请日:
2006.02.17
申请国别(地区):
EP
年份:
2012
代理人:
摘要：
A method for producing an anti-cancer agent based on coordination compounds of platinum (II), under which an aqueous solution containing humic acids is treated with the said platinum compound. The coordination compound of platinum is selected from the following range: potassium tetrachloroplatinate, cis -dichlorodiammineplatinum, hydrogen tetrachloroplatinate, potassium tetrabromoplatinate. The treatment is conducted under irradiation with waves until the concentration of the high molecular fraction of humic substances is brought to a level of 5% or less. The wave radiation is selected from the ultrasonic range, with frequencies from 18 kHz to 66 kHz and power density from 0.5 to 4 W/cm 3 . For 5 W/cm 3 irradiation at the frequency of 22 kHz, the treatment is conducted for 5 to 20 minutes. Irradiation may also be performed with microwaves in the frequency range from 0.3 to 30 GHz and power from 0.5 to 50 kW. For 5 W/cm 3 irradiation at the frequency of 2.45 GHz, the product being treated is maintained at the temperature of 60-70°C for 30 to 90 minutes.
