A LIPOSOME CONTAINING shRNA MOLECULE TARGETING A THYMIDYLATE SYNTHASE AND USE THEREOF

• 收藏
• 分享

专利权人:

发明人:

申请号：

EP12790050.4

公开号：

EP2716304B1

申请日:

2012.05.22

申请国别(地区):

EP

年份:

2017

代理人:

摘要：

This method provides a method for delivering shRNA targeting TS in vivo. In addition, the following is provided: an antitumor agent, which comprises short hairpin RNA (shRNA) capable of inhibiting expression of thymidylate synthase by RNAi action and a PEG-modified cationic liposome, wherein the shRNA is bound to the surface of the PEG-modified cationic liposome and has an overhang comprising at least two nucleotides at the 3 end.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/