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출혈 제어 및 약물 전달을 위한 나노입자
专利权人:
CASE WESTERN RESERVE UNIVERSITY
发明人:
LAVIK ERIN,라빅, 에린,SHOFFSTALL ANDREW,쇼프스털, 앤드류,USTIN JEFFREY,우스틴, 제프리
申请号:
KR1020147012374
公开号:
KR1020140084144A
申请日:
2012.10.12
申请国别(地区):
KR
年份:
2014
代理人:
摘要:
A temperature stable nanoparticle is provided comprising a core, a water soluble polymer and a peptide, the water soluble polymer attached to the core at a first terminus of the water soluble polymer, the peptide attached to a second terminus of the water soluble polymer, the peptide comprising an RGD amino acid sequence, the water soluble polymer of having sufficient length to allow binding of the peptide to glycoprotein lib/Ilia (GPIIb/llla). In one aspect, the nanoparticle has a melting temperature over 35° C. In various aspects, the nanoparticle has a spheroid shape and a diameter of less than 1 micron.중심부, 수용성 중합체 및 RGD 펩티드를 포함하는 나노입자가 제공된다.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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