經取代之核苷、核苷酸及其類似物之用途农业专利-农业学术服务平台

发明人:: WANG, GUANGYI,王刚奇,王剛奇,SMITH, DAVID BERNARD,史密斯　大卫　柏娜德,史密斯　大衛　柏娜德,BEIGELMAN, LEONID,贝奇曼　里欧尼德,貝奇曼　里歐尼德,DEVAL, JEROME,迪维尔　裘洛密,迪維爾　裘洛密,PRHAVC, MARIJA,普莱哈维克　马瑞洁,普萊哈維克　馬瑞潔,史密斯大卫柏娜德,史密斯大衛柏娜德,贝奇曼里欧尼德,貝奇曼里歐尼德,迪维尔裘洛密,迪維爾裘洛密,普莱哈维克马瑞洁,普萊哈維克馬瑞潔

摘要：: Disclosed herein are nucleosides, nucleotides and analogs thereof, pharmaceutical compositions that include one or more of nucleosides, nucleotides and analogs thereof, and methods of synthesizing the same. Also disclosed herein are methods of ameliorating and/or treating a disease and/or a condition, including an infection from a paramyxovirus and/or an orthomyxovirus, with a nucleoside, a nucleotide and an analog thereof.本文揭示核苷、核苷酸及其類似物；包括一或多種核苷、核苷酸及其類似物之醫藥組合物；及其合成方法。本文亦揭示用核苷、核苷酸及其類似物改善及/或治療疾病及/或病況(包括副黏液病毒及/或正黏液病毒感染)之方法。