STEMINENT BIOTHERAPEUTICS INC.;NATIONAL YANG-MING UNIVERSITY
发明人:
CHANG, RYAN,张 志刚,張 志剛,HO, JENNIFER HUI-CHUN,何慧君,LEE, OSCAR KUANG-SHENG,李光申,LIN, NIANG-CHENG,林酿呈,林釀呈,LUI, CHIN-SU,刘君恕,劉君恕
申请号：
TW107131238
公开号：
TW201919665A
申请日:
2018.09.06
申请国别(地区):
TW
年份:
2019
代理人:
摘要：
The invention provides a method for prevention or treatment of acute liver dysfunction with an elevation of serum ammonia, serum creatinine, or INR in a subject, comprising infusion administering a single unit dose of a mesenchymal stem cell population in an effective amount of about 0.5 x 104to about 5 x 106cells/kg body weight to the subject, wherein the serum ammonia, serum creatinine and INR is greater than about 70 μg/dL, about 1.3 mg/dL and 1.2, respectively.本發明提供一種在個體內預防或治療伴隨有血清氨、血清肌酐或INR之升高的急性肝功能障礙的方法，其包含以約0.5×104至約5×106細胞/公斤體重之有效量向該個體輸注投與單個單位劑量之間葉幹細胞群，其中該血清氨、血清肌酐及INR分別大於約70 μg/dL、約1.3 mg/dL及1.2。
