TRAPP, SEAN G.,LEADBETTER, MICHAEL R.,LONG, DANIEL D.,JACOBSEN, JOHN R.,VAN DYKE, PRISCILLA,COLSON, PIERRE-JEAN,RAPTA, MIROSLAV,YU, YING
申请号：
MYPI 2010002437
公开号：
MY149973A
申请日:
2008.12.10
申请国别(地区):
MY
年份:
2013
代理人:
摘要：
THE INVENTION PROVIDES 3-CARBOXYPROPYL-AMINOTETRALIN COMPOUNDS OF FORMULA (I): (I) WHEREIN R1, R2, R3, R4, R5, AND R6 ARE DEFINED IN THE SPECIFICATION, OR A PHARMACEUTICALLY-ACCEPTABLE SALT THEREOF, THAT ARE ANTAGONISTS AT THE MU OPIOID RECEPTOR. THE INVENTION ALSO PROVIDES PHARMACEUTICAL COMPOSITIONS COMPRISING SUCH COMPOUNDS, METHODS OF USING SUCH COMPOUNDS TO TREAT CONDITIONS ASSOCIATED WITH MU OPIOID RECEPTOR ACTIVITY, AND PROCESSES AND INTERMEDIATES USEFUL FOR PREPARING SUCH COMPOUNDS.
