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Moenomycin analogs, methods of synthesis, and uses thereof
专利权人:
Daniel Kahne
发明人:
Daniel Kahne,Suzanne Walker Kahne,Masaatsu Adachi,Emma Doud,Shinichiro Fuse,Xiaonan Lin,Yi Zhang,Hirokazu Tsukamoto,Bohdan Ostash
申请号:
US12681052
公开号:
US08604004B2
申请日:
2008.10.03
申请国别(地区):
US
年份:
2013
代理人:
摘要:
The present invention provides novel moenomycin analogs as well as pharmaceutical compositions thereof, methods of synthesis, and methods of use in treating an infection by administering an inventive compound to a subject in need thereof. The moenomycin analogs may be prepared synthetically, biosynthetically, or semi-synthetically. The analogs are particularly useful in treating or preventing infections caused by Gram-positive organisms. Certain inventive compounds may have a broader spectrum of coverage, which includes Gram-negative organisms.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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