The present disclosure relates to a discharger for discharging a predetermined amount of fluid, in particular a liquid including at least one medical, dental or veterinary, dental or veterinary agent, the discharger comprising a housing (11) defining a longitudinal axis and having a proximal end and a distal end, a discharge device (15) arranged at least partly inside the housing (11) and having an inlet opening (17) situated inside the housing (11) and an outlet opening (19), the discharge device (15) further defining a discharge passage for the fluid extending between the inlet opening (17) and the outlet opening (19), a carriage (21) received in a proximal end region of the housing (11) and being moveable relative to the housing (11) along the longitudinal axis (13) between a starting position and a final discharge position, wherein in the starting position the carriage (21) protrudes from the proximal end of the housing (11) so as to be pushable by a user further into the housing (11) and towards the final discharge position, and wherein the carriage (21) defines a receiving space (23) which is adapted to be loaded with a separate container (25) holding an amount of fluid to be discharged, and activation means (29) for establishing a flow connection for the fluid from within the receiving space (23) of the carriage (21) to the inlet opening (17) of the discharge device (15), the activation means (29) being inoperative when the carriage (21) is in the starting position and being adapted to establish the flow connection when the carriage (21) is in the final discharge position or is being moved towards the final discharge position.