A syringe cap removing device of the present invention includes a seat, a main body, and a clamp. The main body is detachably disposed on the seat with an end and. The clamp is disposed on an end of the main body opposite to the seat. The clamp defines a clamping space for clamping a syringe clamp. Thus, the clamp can be positioned on the seat or be detached from the seat for held by hand so that the present invention helps user remove the syringe cap without touching it directly.