ANTICORPS HUMANISES A LA SOUS-UNITE D'INTEGRINE ANTI-BETA7 ET UTILISATIONS CONNEXES

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专利权人:

GENENTECH; INC.

发明人:

DENNIS, MARK S.,FONG, SHERMAN

申请号：

CA2577678

公开号：

CA2577678C

申请日:

2005.09.02

申请国别(地区):

CA

年份:

2014

代理人:

摘要：

In various aspects, the invention provides for the humanization of the ratanti-beta7integrin subunit monoclonal antibody FIB504, inhibition by such humanizedantibodies of the binding of beta7 subunit-containing integrins to theirligands, anduse of such antibodies in the treatment of certain disorders including, forexample,inflammatory bowel disease, Crohn's disease, ulcerative colitis and otherinflammatory disorders.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/