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Heterotricyclic compounds as serotonergic and/or dopaminergic agents and uses thereof
专利权人:
Vladimir Kogan
发明人:
Vladimir Kogan
申请号:
US12532869
公开号:
US08168639B2
申请日:
2007.09.24
申请国别(地区):
US
年份:
2012
代理人:
摘要:
Novel heterocyclic compounds of formula I:A-B-D  Formula Ior a pharmaceutically acceptable salt thereof,wherein: A is selected from the group consisting of a moiety having general Formula II and a moiety having general Formula III:B is a moiety selected from the group consisting of:D is a moiety selected from the group consisting of:which exhibit a dopamine receptor (preferably a D4 receptor) and/or a serotonine receptor (preferably 5HTA1 agonistic activity), processes of preparing same, pharmaceutical compositions containing same and uses thereof in the treatment of medical conditions associated with the dopaminergic and/or serotonergic systems (e.g., sexual disorders, dyskinesia, anxiety) are disclosed.
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