PROBLEM TO BE SOLVED: To provide a histamine release inhibitor comprising a natural extract having high safety as an active ingredient.SOLUTION: The histamine release inhibitor comprises an extract of Verbena Officinalis as an active ingredient of the histamine release inhibitor and can be used as a medicine, a quasi-medicine and a cosmetic having preventing and ameliorating effects on allergen diseases such as atopic dermatitis, bronchial asthma, pollinosis, etc.COPYRIGHT: (C)2012,JPO&INPIT【課題】安全性の高い天然抽出物を有効成分とするヒスタミン遊離抑制剤を提供する。【解決手段】ヒスタミン遊離抑制剤の有効成分として、クマツヅラからの抽出物を含有せしめる。【選択図】なし
