ALAN OLAGUE,ALESSANDRA BARTOLOZZI,DORIS RIETHER,JOHN D. HUBER,JONATHON ALAN DINES,PUI LENG LOKE,STEPHANE DE LOMBAERT,TINA MORWICK,TODD BOSANAC,WEIMIN LIU,ZHIDONG CHEN
申请号:
BR112013008638
公开号:
BR112013008638A2
申请日:
2011.09.20
申请国别(地区):
BR
年份:
2016
代理人:
摘要:
The present invention relates to compounds of formula (I) and (IA): and pharmaceutically acceptable salts thereof, wherein R1-R5 are as defined herein. The invention also relates to pharmaceutical compositions comprising these compounds, methods of using these compounds in the treatment of various diseases and disorders, processes for preparing these compounds and intermediates useful in these processes.