Joycelyn ENTWISTLE;Glen Christopher MACDONALD;Jeannick CIZEAU;Nicholas Ronald GLOVER;Francina C. CHAHAL
发明人:
Francina C. CHAHAL,Joycelyn ENTWISTLE,Jeannick CIZEAU,Nicholas Ronald GLOVER,Glen Christopher MACDONALD
申请号：
US13297783
公开号：
US20120128723A1
申请日:
2011.11.16
申请国别(地区):
US
年份:
2012
代理人:
摘要：
The present invention provides the amino acid and nucleic acid sequences of heavy chain and light chain complementarity determining regions of a cancer specific antibody. In addition, the invention provides cancer specific antibodies and immunoconjugates comprising the cancer specific antibody attached to a toxin or label, and methods and uses thereof. The invention also relates to diagnostic methods and kits using the cancer specific antibodies of the invention. Further, the invention provides a novel cancer-associated antigen and its uses thereof.
