Jean Francois Zagury;Helene Le Buanec;Daniel Zagury;Bernard Bizzini
发明人:
Jean Francois Zagury,Bernard Bizzini,Helene Le Buanec,Daniel Zagury
申请号:
US11735319
公开号:
US08101165B2
申请日:
2007.04.13
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The invention concerns vaccines comprising as an active principle an immunogen which is a cytokinetic factor or a cell regulating factor particularly transcriptional or another type of factor with immunosuppressive/apoptotic/angiogenic properties abnormally released in the extracellular (stromal) environment by cancer or stromal cells of malignant tumors, and a pharmaceutically acceptable carrier for inducing a systemic or mucosal immune response with secretory formation of class IgC or IgA neutralizing antibodies directed against the native factor, or which is derived from such a factor and the use of said immunogen to obtain a medicine for use as anticancer drug.