The present invention relates to a three-dimensional biomedical device, having an osteoconductive first area with a controlled porosity, which is located at the periphery of the device, surrounding and bordering a second area, the device being produced by a laser technology from a powder comprising ceramics and/or metals and/or metal alloys and/or bioactive glasses and/or lead zirconate titanate and/or biocompatible polymers and/or mixtures thereof, the ratio of the porosity of the second area to the porosity of the first area being equal or less than one, preferably ranging from 0,001 to 0,9. The present invention also relates to a method for manufacturing the said biomedical device.