David Allen Annis,Krzysztof Darlak,Chris Rhodes,Sonoko Kanai,Joerg Hoernschemeyer,Michaela Grass,ANNIS, David Allen,DARLAK, Krzysztof,RHODES, Chris,KANAI, Sonoko,HOERNSCHEMEYER, Joerg,GRASS, Michaela
申请号:
US14864687
公开号:
US20160101145A1
申请日:
2015.09.24
申请国别(地区):
US
年份:
2016
代理人:
摘要:
Aqueous pharmaceutical formulations, for parenteral administration, comprising peptidomimetic macrocycle or a pharmaceutically acceptable salt thereof wherein the peptidomimetic macrocycle binds to MDM2 and/or MDMX proteins are disclosed. Also disclosed are methods of treating diseases and disorders using the aqueous pharmaceutical formulations disclosed herein.