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Branched 3-phenylpropionic acid derivatives and the use thereof
专利权人:
BAYER INTELLECTUAL PROPERTY GMBH
发明人:
STASCH JOHANNES-PETER,KNORR ANDREAS,WUNDER FRANK,LI VOLKHART MIN-JIAN,LAMPE THOMAS,SCHLEMMER KARL-HEINZ,WOLTERING ELISABETH,HAHN MICHAEL,BECKER-PELSTER EVA-MARIA,STOLL FRIEDERICKE
申请号:
NZ61627412
公开号:
NZ616274A
申请日:
2012.03.28
申请国别(地区):
NZ
年份:
2016
代理人:
摘要:
The disclosure relates to 3-phenylpropionic acid derivatives carrying a branched or cyclic alkyl substituent at the 3-position, to methods for the production thereof, to the use thereof for treating and/or preventing illnesses, and to the use thereof for producing pharmaceuticals for treating and/or preventing illnesses, in particular for treating and/or preventing cardiovascular diseases. Examples of compounds of formula (I) are: Methyl 3-(4-chloro-3-{ [(2S,3R)-2-(4-chlorophenyl)-4,4,4-trifluoro-3-methylbutanoyl]amino} phenyl)-5,5-difluorohexanoate; Methyl 3-(4-chloro-3-{ [(2S,3R)-2-(4-chlorophenyl)-4,4,4-trifluoro-3-methylbutanoyl]amino} phenyl)-3-(2,2-difluorocyclopropyl)propanoate and tert-Butyl 3-(4-chloro-3-{ [(2S,3R)-2-(4-chlorophenyl)-4,4,4-trifluoro-3-methylbutanoyl]amino} phenyl)-3-(3,3-difluorocyclobutyl)propanoate.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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