Matthew Colin Thor Fyfe,Michael Knaggs,Premji Meghani,Stephen Malcolm Thom
申请号：
US14424967
公开号：
US20150210722A1
申请日:
2013.08.28
申请国别(地区):
US
年份:
2015
代理人:
摘要：
There are provided compounds of formula (I),wherein R1 to R5, X1, X2, Ar, L, A, A1, E and G have meanings given in the description, which compounds have anti-inflammatory activity (e.g., through inhibition of one or more of members of: the family of p38 mitogen-activated protein kinase enzymes Syk kinase and members of the Src family of tyrosine kinases) and have use in therapy, including in pharmaceutical combinations, especially in the treatment of inflammatory diseases, including inflammatory diseases of the lung, eye and intestines.
