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TC-PTP inhibitors as APC activators for immunotherapy
专利权人:
发明人:
Michel L. Tremblay,Claudia Penafuerte,Matthew Feldhammer,George Zogopoulos,Cameron Black,Brian Kennedy
申请号:
US15122031
公开号:
US09828399B2
申请日:
2015.02.27
申请国别(地区):
US
年份:
2017
代理人:
摘要:
The invention encompasses the novel class of compounds represented by the Formula (I) below, which are inhibitors of the TC-PTP enzyme. The invention also encompasses pharmaceutical compositions which include the compounds shown above and methods of treating or preventing TC-PTP mediated diseases, including cancer, via their use in the activation of antigen-presenting cells, like dendritic cells, for applications in the immunotherapeutic treatment of diseases.
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