PARK, YONG HOONKR,박용훈,EOM, DONG YEOLKR,엄동열,SO, HYEON SUKKR,소현숙,GIM, EUN HYEKR,김은혜
申请号：
KR1020150094579
公开号：
KR1020170005265A
申请日:
2015.07.02
申请国别(地区):
KR
年份:
2017
代理人:
摘要：
By producing multilayer coated microparticles for tissue reconstruction with different crosslinking degree using various ingredients such as hyaluronic acid, the present invention reduces an injecting pressure when objects are injected by operating the outer layer of the tissue reconstruction with low crosslinking degree and delays disintegration when the objects enter the body by operating the inner layer of the tissue reconstruction with high crosslinking degree. So, the retention time for the tissue reconstruction is lengthened. Also, the present invention was completed as the invention improves main problems of existing tissue reconstruction like injection pressure, shape maintenance and the retention time by increasing the shape maintenance with high elasticity of the inner layer.COPYRIGHT KIPO 2017본 발명은 히알루론산 등 다양한 성분들을 이용하여 가교도가 다른 다수층으로 구성된 미립자형 조직수복제를 제조함으로써, 주입 시 적은 가교도의 조직수복제 외각층이 작용하여 주입압력을 줄이고, 체내도입 후 큰 가교도의 조직수복제 내부층이 작용하여 분해작용을 지연시킴으로써 조직수복제의 유지기간이 연장되며 또한, 내부층의 큰 탄성으로 인해 형태의 유지도를 증가시킴으로써 기존 조직수복제들의 주요 문제점인 주입압력, 형태유지 및 유지기간을 개선함으로써 본 발명을 완성하였다.
