PROBLEM TO BE SOLVED: To provide a blood purification apparatus and a calibration method for the blood concentration sensor in the blood purification apparatus in which at least the inclination of the calibration curve of the blood concentration sensor can be calibrated and measurement error can be prevented.SOLUTION: The calibration method includes the first step in which blood is circulated extracorporeally in a blood circuit without performing water removal and a light receiving voltage is detected to obtain a blood concentration based on respective calibration curves, the second step in which the blood is extracorporeally circulated in the blood circuit with the water removal performed and the light receiving voltage is detected to calculate the theoretical blood concentration, the third step in which the relationship of light receiving voltage and the blood concentration of the vein side blood concentration sensor is obtained to calibrate the calibration curve of the vein side blood concentration sensor based on the relationship concerned, and the fourth step in which the calibration curve of the artery side blood concentration sensor is calibrated, based on the relationship of the calibration curve of the vein side blood concentration sensor calibrated by the third step and the calibration curve of the vein side blood concentration sensor before the calibration.COPYRIGHT: (C)2013,JPO&INPIT【課題】少なくとも血液濃度センサの検量線の傾きを校正することができ、測定誤差を抑制することができる血液浄化装置及び血液浄化装置における血液濃度センサの校正方法を提供する。【解決手段】除水を行わない状態で血液回路にて血液を体外循環させるとともに、受光電圧を検出し、それぞれの検量線に基づき血液濃度を得る第1工程と、除水を行った状態で血液回路にて血液を体外循環させるとともに、受光電圧を検出し、且つ、理論上の血液濃度を算出する第2工程と、静脈側血液濃度センサの受光電圧と血液濃度との関係を得るとともに、当該関係に基づいて静脈側血液濃度センサの検量線を校正する第3工程と、第3工程により校正された静脈側血液濃度センサの検量線と校正前の静脈側血液濃度センサの検量線との関係に基づき、動脈側血液濃度センサの検量線を校正する第4工程とが行われるものである。【選択図】図8
