NAKACHE, Philippe,EREZ, Omri,BOTTI, Simone,GOUTOPOULOS, Andreas,LABELLE, Marc
申请号：
SG11202004318P
公开号：
SG11202004318PA
申请日:
2018.11.15
申请国别(地区):
SG
年份:
2020
代理人:
摘要：
The present invention relates to novel ACSS2 inhibitors having activity as anti-cancer therapy, treatment of alcoholism, and viral infection (e.g., CMV), composition and methods of preparation thereof, and uses thereof for treating viral infection, alcoholism, alcoholic steatohepatitis (ASH), non-alcoholic steatohepatitis (NASH), obesity/weight gain, anxiety, depression, post-traumatic stress disorder, inflammatory/autoimmune conditions and cancer, including metastatic cancer, advanced cancer, and drug resistant cancer of various types.
