PROBLEM TO BE SOLVED: To provide a guide sheath whereby a plurality of insertion members can be easily guided into a body cavity.SOLUTION: A tubular guide sheath 1 for guiding insertion members of a medical instrument that is to be inserted into the body cavity, the guide sheath 1 comprising: an opening 11 in the base-end side which is formed in the base-end side of a guide sheath body 10 and through which a plurality of insertion members are led in an opening 12 in the fore-end side which is formed in the fore-end side of the guide sheath body 10 and through which a plurality of insertion members are led out and an adjusting mechanism 30 which adjusts the opening area of the opening 12 in the fore-end side.COPYRIGHT: (C)2013,JPO&INPIT【課題】複数の挿入部を体腔内に容易に誘導することができるガイドシースを提供する。【解決手段】体腔内に挿入される医療器具の挿入部を誘導する筒状のガイドシース1であって、ガイドシース本体10の基端側に設けられ、複数の挿入部が導入される基端側開口部11と、ガイドシース本体10の先端側に設けられ、複数の挿入部が導出される先端側開口部12と、先端側開口部12の開口面積を調整する調整機構30とを備えるガイドシース1を採用する。【選択図】図1