PROBLEM TO BE SOLVED: To provide a platelet-derived growth factor-BB (PDGF-BB) production accelerator that contributes to promotion of production of a mesenchymal stem cell and to stabilization of a stem cell, and a stem cell stabilizer comprising the production accelerator.SOLUTION: The PDGF-BB production accelerator comprises as an effective ingredient at least either one of extract of amla which is a deciduous middle shrub/sub-tall tree belonging to the genus Emblica of the family Euphorbiaceae and extract of lingonberry (commonly called cowberry) which is an evergreen undershrub belonging to the genus Vaccinium of the family Ericaceae. The stem cell stabilizer comprises the production accelerator.【課題】間葉系幹細胞の産生促進や幹細胞の安定化に寄与する血小板由来成長因子－ＢＢ（ＰＤＧＦ－ＢＢ）の産生亢進剤、および該産生亢進剤を含有する幹細胞安定化剤の提供。【解決手段】トウダイグサ科エンブリカ属に属する落葉中低木亜高木であるアムラ抽出物及びツツジ科スノキ属の常緑小低木であるリンゴンベリー抽出物（通称：コケモモ）の少なくともいずれかを有効成分として含んでなるＰＤＧＦ－ＢＢ産生亢進剤、および該産生亢進剤を含有する幹細胞安定化剤。【選択図】なし
