EISCHEN, KATHLEEN, A,ANDERSON, CARTER, R,MORRIS, RUSSELL, L
申请号：
NZ59133309
公开号：
NZ591333A
申请日:
2009.08.31
申请国别(地区):
NZ
年份:
2012
代理人:
摘要：
Disclosed is a wearable iontophoresis device for the prolonged delivery of a positively charged pharmaceutical species from a salt formulation (such as donepezil hydrochloride) comprising: (a) a readily oxidisable metal-based sacrificial anode (such as silver) in the form of a generally planar layer having a connecting neck area that has a width that is generally 5% or more of the maximum electrode width dimension such that said sacrificial anode will remain connected for the desired operating life of the sacrificial anode wherein the sacrificial anode is configured to have a minimum operating life of at least 6 hours under skin-safe conditions and is entirely consumed during the prolonged operation of the sacrificial anode and (b) a drug delivery gel pad in electrical contact with said anode for accommodating a gel containing a positively charged pharmaceutical species in salt form formulated for transdermal delivery.
