HOOD JOHN,WALLACE DAVID MARK,KC SUNIL KUMAR,HOOD John,WALLACE David Mark,KC Sunil Kumar
申请号：
SI201031084
公开号：
SI2464232T1
申请日:
2010.08.09
申请国别(地区):
SI
年份:
2016
代理人:
摘要：
Indazole compounds for treating various diseases and pathologies are disclosed. More particularly, the present invention concerns the use of an indazole compound or analogs thereof, in the treatment of disorders characterized by the activation of Wnt pathway signaling (e.g., cancer, abnormal cellular proliferation, angiogenesis, Alzheimer's disease and osteoarthritis), the modulation of cellular events mediated by Wnt pathway signaling, as well as genetic diseases due to mutations in Wnt signaling components. Also provided are methods for treating Wnt-related disease states.
