Polymer nanoparticle finasteride, Aqueous suspension containing the same, and composition for treating alopecia, Process for preparing Said Composition and its use
Pharmaceutical composition for the treatment of alopecia, the composition contains a polymeric nanocapsules containing Nanoparticles, preferably, finasteride, Additives and pharmaceutically acceptable vehicle. Use of Nanoparticles for the preparation of such a composition for the treatment of alopecia.Process for the preparation of nanocapsules or appropriate vehicle for a composition for the Topical Treatment of alopecia.Claim 1: nanoparticle Polymer characterized by adding the active substance finasteride, being that the nanoparticle is formed from the preparation of an organic phase and an aqueous Phase, in which: (a) The Organic Phase comprises: (i) a Hydrophobic Polymer, (ii) an AC Eite or mixture of Oils, (iii) at least one lipophilic Surfactant under EHL, (iv) a Solvent,Finasteride, and (V) and (b) the aqueous Phase comprises: (i) at least a Hydrophilic Surfactant, and (vii) Water. Claim 3: nanoparticle Polymer according to claim 1, characterized by the fact that the Hydrophobic Polymer is selected from the group consisting of vinyl Polymers, Polyesters, Polyamides, polycarbonates and poliuretanas, Acrylic Polymers.Claim 11: nanoparticle Polymer according to claim 7, characterized by the fact that the Mixing of Oils are triglycerides and caprylic and capric acids mixture of linalool and Farnesol.Composición farmacéutica para el tratamiento de la alopecia, dicha composición contiene nanopartículas poliméricas, preferencialmente nanocápsulas, conteniendo finasterida, aditivos y vehículo farmacéuticamente aceptables. Uso de las nanopartículas para preparar dicha composición para el tratamiento de la alopecia. Proceso de preparación de nanocápsulas de finasterida apropiadas para una composición de vehículo tópico para el tratamiento de la alopecia. Reivindicación 1: Nanopartícula polimérica caracterizada por incluir el principio activo finasterida, siendo que dicha nanopartícula es formada a partir de la preparación de una fase orgánica y una fase acuosa, en que: