Magnoliidae compounds are made by obtaining parts of Magnoliidae plants. The parts of the Magnoliidae plants are mixed with alcohol and water. The mixture of the parts of the Magnoliidae plants, alcohol and water is heated and the parts of the Magnoliidae plants are removed so that a liquid mixture remains. The liquid mixture is drying to form a solid composition. Alcohol and water are added to the solid composition to reconstitute the solid composition into a liquid composition. The liquid composition is heated to form solid matter. The solid matter is dried to obtain a purified composition of the Magnoliidae compounds. A dose of Magnoliidae compounds promotes weight loss and can be administered in liquid form, sublingually, intravenously, in a pharmaceutically acceptable carrier, in combination with a metabolite detoxification agent, in combination with a nutritional or dietary supplement, or in chewing gum.