HRUBY, DENNIS, E.,BOLKEN, TOVE, C.,AMBERG, SEAN, M.,DAI, DONGCHENG,LARSON, RYAN, A.
申请号:
EP09816619
公开号:
EP2291184A4
申请日:
2009.04.29
申请国别(地区):
EP
年份:
2012
代理人:
摘要:
Compounds, methods and pharmaceutical compositions for treating viral infections, by administering certain novel compounds in therapeutically effective amounts are disclosed. Methods for preparing the compounds and methods of using the compounds and pharmaceutical compositions thereof are also disclosed. In particular, the treatment and prophylaxis of viral infections such as caused by hemorrhagic fever viruses is disclosed, i.e., including but not limited to, Arenaviridae (Junin, Machupo, Guanarito, Sabia, Lassa, Tacaribe, Pichinde, and LCMV), Filoviridae (Ebola and Marburg viruses), Flaviviridae (yellow fever, Omsk hemorrhagic fever and Kyasanur Forest disease viruses), and Bunyaviridae (Rift Valley fever and Crimean-Congo hemorrhagic fever).