To provide a versatile controlled drug delivery system, free of problems such as poor water solubility or agglomeration.SOLUTION: The present invention provides a nanoparticle having a solid core comprising a biologically active substance, said core being enclosed by an inorganic coating, a method for preparing the nanoparticle, and the use of the nanoparticle in therapy. There are also provided a kit comprising the nanoparticle and a pharmaceutical composition comprising the nanoparticle.SELECTED DRAWING: None【課題】水溶性の乏しさや凝集等の問題点がない、多目的の制御薬物送達系を提供する。【解決手段】生物学的に活性な物質を含んでなる固体コアを有するナノ粒子、無機物コーティングによって包まれている前記コア、ナノ粒子を製造するための方法、及び治療におけるナノ粒子の使用。ナノ粒子を含んでなるキット及びナノ粒子を含んでなる医薬組成物。【選択図】なし
